Increasing Demand for Nucleic Acid Isolation and Purification as Application Areas Expand

The first step in the field of molecular biology research, along with recombinant techniques, is nucleic acid separation and purification. Enzymatic digestion, mechanical and chemical disruption, and nucleic acid isolation are the main steps in this method.

Scientists and researchers can receive high-quality materials for conducting downstream applications and producing accurate results thanks to the benefits provided by nucleic acid separation and purification.

The market for nucleic acid isolation and purification has been deemed to benefit from COVID-19’s current effects. The need for DNA/RNA isolation and purification kits has expanded significantly due to the current necessity for sophisticated and high-throughput solutions for sample testing.

A number of new products have been introduced as a result of the rise in demand for nucleic acid-based diagnostics, which has also prompted the development of automated bench-top instruments, sample collection tools, and quick methods for preparing nucleic acid samples.

According to the market intelligence report on Global Nucleic Acid Isolation and Purification Market published by BIS Research, the global nucleic acid isolation and purification market was estimated at $2,304.7 Million in 2020 and is expected to grow at a CAGR of 7.20% from 2021 to 2031.

This growth is attributed to factors such as the rise in the field of microbial sequencing, increasing research funding in the field of molecular biology, increase in awareness and acceptance of personalized medicines on a global level, and decreasing cost of sequencing.

Automation has made it easier for end users to conduct a wide range of applications, including those involving genomic/plasmid DNA, cell-free DNA (cfDNA), viral RNA, and cell-free RNA. Nucleic acid isolation and purification allowed end users to conduct a wide range of applications (cfRNA).

The advantages of genomic/plasmid DNA extraction include the use of quick, easy processes that reduce the amount of time DNA is exposed to pollutants and, as a result, slow down the pace of degradation.

The isolation of cfDNA is majorly used in the field of non-invasive prenatal testing (NIPT) and precision oncology as cfDNA contains ctDNA, which is further utilized in the process of molecular analysis. Therefore, the isolation efficiency becomes critical for efficient ctDNA analysis utilizing downstream applications, particularly for disease detection.

Automation in nucleic acid separation and purification also provides great throughput, lowering sample processing time further. The adoption of automated nucleic acid isolation and purification products is further supported by factors like the rising prevalence of genetic diseases, expanding molecular biology research, growing awareness and acceptance of precision medicine globally, and rising research funding from public and private institutions.